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This article examines occupational health and safety (OHS), with a particular focus on youth apprentices. It uses quantitative and qualitative data to examine the incidence of injuries among youth apprentices, and their experiences related to health and safety at work in Canada. Analysis of large-scale national surveys suggests a high incidence of work-related injuries among youth and low participation rates of younger workers in formal OHS training. A survey of 173 former Ontario Youth Apprenticeship Program (OYAP) and Registered Apprenticeship Program in Alberta (RAP) participants finds that one-fifth suffered serious occupational injuries, which required time off work. The results from this study have important implications for youth apprenticeship programs, particularly the OHS- and trade-specific knowledge required for youth to work safely during and following their apprenticeship training.