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A study consists of absenteeism measures for a group of prison guards who switched from an 8-hour work day to a 12-hour day compressed workweek (CWW) schedule with absenteeism measures for one year prior to the onset of the schedule and 2 years on the new schedule. Absenteeism data were compared between the CWW group and a comparison group of regular schedule guards and between the pre-CWW and CWW periods. Absenteeism levels were higher for the CWW group compared to the comparison group, and were higher over the CWW period when compared to the pre-CWW period. In the best specified models, those guards on the CWW had higher absenteeism than the comparison group, though the latter difference was not statistically significant.