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In recent years, the attractiveness of temporary placement agencies for nurses has grown significantly. In a labour scarcity context, it is worth exploring the motivations that encourage nurses to choose temporary work and remain loyal to their agency. Building on the classification of Tan and Tan (2002), four sources of motivation were explored: individual or family incentives, economic incentives, professional motivations and personal preferences. Regarding family motivations, this study was mainly interested in the role of flexible working conditions offered by placement agencies. Concerning economic motivations, we examined the influence of pay conditions. Our investigation of professional motivations centered on agency nurses' opportunities for skills development. Finally, the role of personal preferences was explored via workload. The results of our study, conducted on two samples, one of 500 nurses working in nursing agencies in Quebec and the other of 99 nurses from two agencies, showed that family and professional development motivations had a positive influence on agency nurses' satisfaction. In contrast, their loyalty is more closely related to the need for flexible hours, training and skills development, job security and the possibility of choosing one's assignments. Good salary conditions are not sufficient. Nurses who choose temporary work are motivated by more than a quest for better economic conditions. They also want greater freedom of choice and self-determination, and more opportunities for professional development.